End-to-End Bioprocessing Solutions: From Upstream to Downstream
From development to delivery — we make your fermentation journey faster and easier
THE FLEX ADVANTAGE
Where Flexibility Meets Scale in Bioprocessing
Flex BioCulture is your agile and flexible partner for fermentation development and scale-out. We provide end-to-end support with expertise in upstream, downstream, and analytical services, giving you the capacity and technical depth to move faster. Our scalable infrastructure and collaborative, scientist-to-scientist approach ensure that processes are optimized and tailored to your needs. When ready, we connect you with trusted CDMO/CMO partners for seamless tech transfer and larger-scale manufacturing. With Flex BioCulture, you gain a partner committed to de-risking development and accelerating your path to commercialization.
Full Visibility & Collaborative Insights
We provide complete access to raw data at the end of each run and work closely with you as an extended team. This collaborative approach ensures you have the information and support needed to make informed, confident decisions every step of the way.
Hands-On Project Partnership
Our team provides hands-on support throughout your project, guiding you from concept to commercialization. With dedicated oversight, expert coordination, and personalized attention, we keep your project running smoothly and on schedule.
Flexible, No-Risk Engagement
No monthly or annual fees, no minimum runs—our cost-effective, adaptable model lets you scale services to your needs without commitment, giving you efficiency and freedom to move faster.
Broad Industry Coverage
​We support a wide range of industries, including biopharma, nutraceuticals, specialty enzymes, agricultural biochemicals, and bio-based ingredients. Our experience across diverse sectors ensures tailored solutions that meet the unique challenges of your market.
Upstream Process Development
Comprehensive Process Development
From strain selection and media optimization to fermentation strategy design
Flexible Fermentation Modes
Expertise in batch, fed-batch, and continuous processes to match project needs
Scalable Fermentation Platforms
Development-scale bioreactors (500mL - 7L) with pathways to pilot and manufacturing
Advanced Process Control
Automated control of pH, DO, temperature and foam
Broad Host Expertise
Proven capabilities with bacterial, yeast, fungal and plant cell systems
Custom Process Engineering
Tailored upstream strategies including optimized feeding regiments, and bioreactor configurations to meet unique performance targets
Downstream Process Development
Clarification & Recovery
Centrifugation and filtration platforms optimized for diverse product stream
Membrane-Based Processing
Tangential Flow Filtration (TFF) for concentration and diafiltration across multiple scales
Protein Purification
Chromatography methods tailored for enzymes, proteins, and specialty molecules
Formulation & Stabilization
Lyophilization and buffer optimization to enhance product stability and shelf life
Analytical Lab
Seamless testing support across the entire process — from metabolites to final product analysis
We are equipped with advanced analytical tools, including the YSI 2950 Biochemistry Analyzer, Reverse Phase HPLC with UV detection, Flow Cytometer, MiniSeq, Zetasizer Nano HT, SpectraMax iD3 Microplate Reader, and iBright 1500 Imager.
Experts in analytical techniques for protein identification and quantification such as SDS PAGE, Western Blot, and ELISA
